Tobacco is the greatest cause of cardiovascular and respiratory diseases and premature death. In this article we describe the
efficacy of an easily applicable medical approach of; (a) thrice-daily tobacco-use for 1 month in heavy smoker that represent
gradual tapering of habit and nicotine-dependence, (b) pulmonary and cardiovascular risk-identification at entry, and (c)
medical rewarding, with disease stability, in tobacco-cessation after 1, 3 and 6 months. In the study we evaluated the efficacy of
such protocol in 200 heavy-smokers that had failed previous drug-therapy and conventional counselling. Patients were
subdivided into 4 matched groups of patients with: (a) chronic obstructive pulmonary disease (COPD), (b) cardiovascular
diseases (CVD), (c) combined COPD & CVDs, and (d) those without them. The overall results indicated >90% cessation rate
after 3 and 6 months yet was 74 and 87% in those without such diseases. In conclusion, tobacco cessation can be achieved,
especially in high-risk patients, with such easily applicable medical protocol.