The well-being state could be influenced by harmonic sounds in music or singing. Preferred music could give joy, compared to classical music that induced mostly relaxation. Medical Resonance Therapy Music® originated from Peter Hubner in Germany uses the theory of resonance, with sonic (20-2000 Hz) and subsonic frequency (0.034-5 Hz) synchronizing with cellular rhythm and restoring auto-healing capacity. An appropriate frequency of music can induce a state of relaxation with effect on reducing stress and restoration of different functions, including neuro-endocrine ones.