Abstract

Objectives: To explore the feasibility of MRU (Magnetic Resonance Urography) under the intravenous injection of furosemide (FRS) in the diagnosis of abnormal hydronephrosis caused by renal pelvis and ureteral junctions during the intermittent period, though a 1.5T magnetic resonance scanner. Study Design: Clinical research. Place and Duration of Study: Department of Radiology and Urology, Children's Hospital of Zhejiang University School of Medicine, Hangzhou, China, from April to September 2019. Methods: Twenty-four children, with symptomatic hydronephrosis caused by abnormal pelvic ureteral junctions during the intermittent period, were scanned by MRU after the first static hydration and the second intravenous injection of FRS, and contrast with ultrasound (US) results. Then comparison with the pathological results for who undergoing surgical treatment. The US and MRU image development was evaluated on a 4-point scale for renal pelvis and ureter development, and the overall situation was evaluated on a 5-point scale. Results: BUS had 70.8% sensitivity of hydronephrosis, 16.7% sensitivity of ureteral dilatation, and overall sensitivity of 70.8%. The sensitivity of the three indexes in the hydraulic group was 87.5%, 95.8% and 100%, respectively. For the FRS group, the sensitivity increased to 100%, and when comparison with the pathological results from the 13 out of 24 cases underwent surgical treatment, the positive rate of coincidence was 77%.