Abstract

Melanoma (from Greek—melas: “dark”) is a tumor originated from malignant transformation of melanocytes (i.e., melanin pigment-producing cells) that can be found in the skin, bowel, and eye [1,2]. According to the American Cancer Society’s estimates for melanoma in the United States for 2022 [3] about 100,000 new melanomas will be diagnosed and about 8000 people are expected to die of melanoma (twice more men). The rates of melanoma have been rising rapidly over the past few decades, but this has varied by age.