Allergic, Cardiovascular and Psychiatric Comorbidities in Adult AD Patients -A Brazilian Study

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Abstract
Introduction: atopic dermatitis (AD) can be associated with allergic diseases such as rhinitis, asthma and food allergies. Recently, it has been be considered a systemic disease, with neuropsychiatric, cardiovascular (dyslipidemia, obesity and hypertension) and neoplasms as comorbidities. Objectives: to analyse the prevalence of AD comorbidities in adult patients at a dermatological center. Methods: retrospective, cross-sectional, comparative study using medical records of adult dermatological patients, between 2018 and 2019. The following comorbidities were investigated: rhinitis, asthma, food allergy, hypertension, obesity, depression and anxiety. Results: allergic comorbidities were shown to be statistically higher in the atopic dermatitis group, for all of the diseases studied (p <0.05). Regarding cardiovascular and psychiatric comorbidities, there was no statistically significant difference between atopic and non-atopic groups. Study Limitations: unicentric study with small number of patients. Conclusions: allergies were more prevalent in the AD population compared to the control group, which should be considered while investigating dermatitis in adults, even though there is no history of juvenile atopy. There was no higher prevalence of the comorbidities investigated in the atopic group in comparison to the control group. However, the prevalence of psychiatric comorbidities was high, in consonance with the current literature, reinforcing the importance of a detailed investigation in adult patients with AD.
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