Abstract
                                        Introduction: atopic dermatitis (AD) can be associated with allergic diseases such as rhinitis, asthma and food allergies. 
Recently, it has been be considered a systemic disease, with neuropsychiatric, cardiovascular (dyslipidemia, obesity and 
hypertension) and neoplasms as comorbidities. Objectives: to analyse the prevalence of AD comorbidities in adult patients at 
a dermatological center. Methods: retrospective, cross-sectional, comparative study using medical records of adult 
dermatological patients, between 2018 and 2019. The following comorbidities were investigated: rhinitis, asthma, food 
allergy, hypertension, obesity, depression and anxiety. Results: allergic comorbidities were shown to be statistically higher in 
the atopic dermatitis group, for all of the diseases studied (p <0.05). Regarding cardiovascular and psychiatric comorbidities, 
there was no statistically significant difference between atopic and non-atopic groups. Study Limitations: unicentric study 
with small number of patients. Conclusions: allergies were more prevalent in the AD population compared to the control 
group, which should be considered while investigating dermatitis in adults, even though there is no history of juvenile atopy. 
There was no higher prevalence of the comorbidities investigated in the atopic group in comparison to the control group. 
However, the prevalence of psychiatric comorbidities was high, in consonance with the current literature, reinforcing the 
importance of a detailed investigation in adult patients with AD.