Allopurinol-Induced Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Successfully Treated with a Single Dose of Etanercept

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Abstract
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are potentially fatal cutaneous adverse reactions usually triggered by medications, allopurinol is frequently associated with this condition, affecting skin and mucous membranes. It typically occurs within days or weeks after the drug’s use [1-3]. Scientific evidence suggests that etanercept may be a promising treatment [2].
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