Abstract

Atopic dermatitis (AD) is a chronic relapsing inflammatory skin disease characterized by recurrent eczematous skin lesions and intense itching. Globally, it affects 10%-30% of children and 2%-10% of adults, with a two- to three-fold increase in prevalence noted over the last decades [1]. AD pathogenesis is multifactorial, and involves a complex interaction between environmental factors, genetics, the immune system, and other factors such as microbiome, which contribute to skin barrier dysfunction and inflammation [2-4].