Abstract
We are experiencing great advances in the medical field that help in early diagnosis of rectal cancer that tend to reduce the
patient’s morbidity and mortality, instead early prognosis, screening protocols greatly improved the overall patient’s wellbeing. However, it should always be taken into account that pathological biopsies have varying rates of specificity and
sensitivity, therefore we should not only rely on pathological findings solely but patients clinical presentation still remains
a gold standard for treatment setup. We can see from this case that we will not only depend on the preoperative biopsy
pathological results, many cases with repeated multiple biopsies with benign lesions, however post resection pathology
showed adenocarcinoma. Therefore, we should also depend on the clinical symptoms as well as on the scope finding
indicating the ''L'' defined shape obstructing the lumen. In this case study, I will be presenting a case that was admitted
and diagnosed in King Faisal Specialist Hospital and Research center that clearly revealed that biopsy does not always
rule out malignancy.