Abstract
In the skin aging process, both intrinsic alterations, secondary to the loss of cell regeneration capacity resultant from
chronological action and extrinsic alterations, mainly caused by the exposure to ultraviolet radiation, can be observed and
change the tissue architecture and skin physiological properties. The treatments that restore the collagen production and
stimulate fibroblasts to synthesize and organize the extracellular matrix is critical for morphogenesis, angiogenesis and skin
healing.
Biostimulation is the ability of a polymer to provide cell benefits or tissue response through specific clinical applications. The
potential use of products that stimulate the production of collagen, a component that plays a fundamental role in the properties
of the extracellular matrix, nowadays represents a promising perspective for the improvement of skin quality and its
mechanical properties by introducing a new concept of therapeutic approach when treating changes caused by skin aging. Its
clinical effects are due to the stimulation of a desired controlled inflammatory response, which leads to the slow degradation
of the material and culminates with the deposition of collagen in the tissue.