Abstract

Adams-Oliver Syndrome is characterized by the combination of aplasia cutis congenita and limb anomalies. It was initially described in 1945 by Adams and Oliver. Different clinical phenotypes may be related to variable severity both of aplasia cutis and terminal transverse limb defects, and of minor clinical features as cutis marmorata telangiectatica congenita, congenital cardiac defect and vascular anomalies. We, herein, describe a case of 3-month-old girl with aplasia cutis, cutis marmorata telangiectatica and terminal transverse limb reduction defects.