Heart Involvement in Hemoglobinopathies: Two Case Reports and Brief Review of Literature
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Abstract
Τhe two main determinants of cardiovascular phenotype in haemoglobinopathy patients are the underlying molecular defect responsible for the main disease and the therapy applied for its management. The spectrum of cardiovascular manifestations in haemoglobinopathies is wide and includes ventricular dysfunction, pulmonary hypertension, thromboembolic events. We report a case of thalassemia and one of sickle cell disease having different clinic phenotype with brief literature review.
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