Abstract

It is proposed that inflammation of capillaries and post-capillary venules constitute a powerful integer of profile progressiveness in MS patients with the added premises of induced agonist action and responding reaction as borne out by the oscillatory nature of the disease process. An ongoing reformulation of gene expression profiles are confirmatory item provocation within the chemical network reactivity as substantially redefined by clinical relapse/remitting disease course. The conformational identity of MS injury is compound derivative within systems of proposed formulas for potential alternation of system biology that comprises the vasculitis of induced phenomena as projected by profiles of additional injury to oligodendrocytes and neurons on the one hand and of demyelination on the other.