Abstract
Extradural Plasmocytoma (EDP) is only known from a small number of cases with poor prognosis, so the clinical
characteristics, treatment protocol, prognostic factors, and natural course remain unclear [1]. Plasmocytoma is a rare lesion
that accounts for 5% of all plasma cell neoplasms [2]. Few case reports have been published with similar characteristics
(TABLE 1). We present a 54-year-old female patient with a solitary but broad lesion with compressive myelopathic
symptoms and an insidious clinical onset. The results may suggest that initial surgical intervention followed by radiotherapy
is beneficial for symptomatic relief of EDP patients. EDP should be included in the differential diagnosis of any extradural
lesion. Hemilaminectomy showed to be effective for symptomatic relief and neurological improvement in the acute onset of
spinal cord compression, but radiotherapy has proven to be successful in preventing relapse. Further research is necessary to
establish treatment recommendations.