Abstract

This is a case of a 28-year-old woman who was admitted in the Subfertility Department of our hospital. She was trying to conceive naturally for 2 years with unprotected, coordinated sexual intercourse. Her hormonal levels showed high FSH 35 IU/L, low estradiol 6 IU/L and hypomenorrhea, so she fulfilled the criteria for Premature Ovarian Failure (POI) diagnosis. She was monitored via Ultrasound to check her ovulation and we prescribed daily fertility supplements with riboflavin (Vitamin B2), niacin (Vitamin B3), pyridoxine (Vitamin B6), 5-methyltetrahydrofolate (activated Vitamin B9), methylcobalamin (activated Vitamin B12), zinc, betaine and L-cystine. After 2 months she conceived naturally, she had an uncomplicated pregnancy and delivered naturally a healthy newborn. To conclude, although POI is a rare diagnosis, with bad prognosis for natural conception, there are therapeutic approaches to help with infertility.