Abstract

Background: Atopic dermatitis is a chronic itchy inflammatory skin condition. Adults account for about 10% of all sufferers. However, those patients usually have the more intense and complicated course. Their life is usually affected physically, and physco-socially. Radioallergosorbent testing (RAST) is a test to measure Immunoglobulin E (IgE) to possible trigger or contributing factors to flare up of atopic dermatitis. Aim: The aim of this study is to evaluate the relevance of RAST testing in the management of adult patients with atopic dermatitis. Method: Standard RAST testing was requested from 81 adult patients referred to the Royal Wolverhampton NHS Trust (Secondary Care). Allergens tested include house dust mite, dairy products, dog dander, cat epithelium, grass, pollens, nuts, seafood and cereals. Results: 51 out of 81 patients (62.9%) showed a higher IgE Level. Results of individual specific IgE level among those patients who tested positive was as follows, starting with the highest, house dust mite (66.6%), grass (58%), cat epithelium (32.1%), dog dander (29.6%), nuts (11.1%), egg (9.8%), cow’s milk/dairy (4.9%), wheat/soya (1.2%). As for the severity level of IgE measured for the scoring levels above 52.50 (IU/ml), Grade 5 and 6, house dust mite (19.7%) grass (5.8%). In the moderate grading of severity (3.5-52.49 IU/ml) Grade 3 & 4 cat epithelium (29.6%), house dust mite (18.5%), dog dander (20.9%), grass (9.8%), fish/seafood (4.9%) and nuts (3.7%). Conclusion: RAST testing is a valuable tool in the management of adult atopic dermatitis and should be considered as part of the management plan.